miRNAs: Key Players in Neurodegenerative Disorders and Epilepsy
نویسندگان
چکیده
منابع مشابه
Circulating miRNAs as biomarkers for neurodegenerative disorders.
Neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD) and frontotemporal dementias (FTD), are considered distinct entities, however, there is increasing evidence of an overlap from the clinical, pathological and genetic points of view. All neurodegenerative diseases are characterized by neuronal loss and death in specific areas of the brain, for example, hippoc...
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Micro RNAs (miRNAs) are a class of 21-24 nucleotide long single stranded, endogenous, noncoding RNAs involved mainly in post transcriptional gene silencing in animals and plants. Their role in the gene regulation of plant growth and development, biotic and abiotic stress responses, methylation is revealed and much more is expected by these tiny molecules. With each passing day a new insight abo...
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Recently, microRNAs (miRNAs) are reported to be crucial modulators in the pathogenesis and potential treatment of epilepsies. To date, several miRNAs have been demonstrated to be significantly expressed in the epileptic tissues and strongly associated with the development of epilepsy. Specifically, miRNAs regulate synaptic strength, inflammation, neuronal and glial function, ion channels, and a...
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ژورنال
عنوان ژورنال: Journal of Alzheimer's Disease
سال: 2015
ISSN: 1387-2877,1875-8908
DOI: 10.3233/jad-150395